Advancing Treatment Strategies in Advanced Systemic Mastocytosis: Integrating Emerging Evidence Into Clinical Practice.
Learning Objectives
- Review current evidence and new therapies for the treatment of AdvSM with a focus on SM-AHN
- Evaluate key patient-specific factors (e.g., tumor characteristics, comorbidities, genetic markers, and performance status) that influence treatment selection in patients with SM-AHN..
- Apply evidence-based strategies to optimize individualized care with patient cases
Why Attend?
Advanced Systemic Mastocytosis (AdvSM) presents significant diagnostic and treatment challenges, particularly in patients with SM‑AHN. This live, expert‑led webinar provides an evidence‑based update on AdvSM, exploring emerging clinical data and practical strategies for integrating new targeted therapies into patient‑centered care.
Event Co-Chairs
Chair
Stephanie Lee
MD, MSc, FRCPC
Dr. Stephanie Lee is a hematologist at St Michael’s Hospital and assistant professor at the University of Toronto.
Speaker
Deepti Radia
MD
Dr Deepti H Radia, Haematology Consultant,
Guy’s & St Thomas’ Hospitals NHS Foundation Trust, London.UK.
Deepti Radia, MRCPI, FRCPath, MSc Med Ed.
Deepti has been in her consultant post at Guys and St Thomas Hospitals since 2003 working in the MPN service.
Deepti is the lead clinician for the systemic mastocytosis and chronic myeloid leukaemia services. The ECNM UK mastocytosis centre of excellence at Guys and St Thomas Hospitals was jointly established by Deepti and Dr Clive Grattan in 2005. This nationally recognised service accepts referrals from across the UK and Ireland.
She is CI/PI for landmark trials for patients with advanced/ symptomatic indolent systemic mastocytosis – PKC412, EXPLORER, PATHFINDER, APEX,PIONEER and HARBOR. She is a member of the study steering committee for the EXPLORER/PATHFINDER trials (Avapritinib in advanced SM) and APEX / SUMMIT trials (Bezuclastinib) for patients with advanced and symptomatic indolent SM.
Deepti is actively involved in the education of clinicians and patients improve understanding of mast cell disorders and delivers regular teaching in regional, national, international meetings in addition to the UKMasto.org and TMS patient support groups.
Speaker
Minakshi Taparia
MBBS, MD, FRCPath
Hematologist Minakshi Taparia graduated from Medical College in Mumbai University in Mumbai, India. She subsequently completed training in clinical and laboratory hematology in Australia and a clinical and laboratory hematology fellowship in the UK. She also has specialized training in bone marrow transplantation. She joined the Division of Hematology at the University of Alberta in 2006, as staff and was promoted to clinical professor in 2023. She has an interest in rare disorders including Mastocytosis, CTCL, Castleman and Histiocytic disorders.
This program has been made possible through unrestricted support from Medison.