Best of ASCO® Montreal 2024: Lower GI – Dr. Petr Kavan

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Co-Chairs
Dr. Jamil Asselah
Dr. Kim Ma

Speakers
Dr. Petr Kavan
Studies/trials discussed:
- Chemotherapy and liver transplantation versus chemotherapy alone in patients with definitively unresectable colorectal liver metastases: A prospective multicentric randomized trial (TRANSMET).
- The ORCHESTRA trial; A phase III trial of adding tumour debulking to systemic therapy versus systemic therapy alone in multi-organ metastatic colorectal cancer (mCRC)
- Colorectal liver metastases: surgery versus thermal ablation (COLLISION) a phase III single-blind prospective randomized controlled trial
- Panitumumab Plus Fluorouracil and Folinic Acid Versus Fluorouracil and Folinic Acid Alone as Maintenance Therapy in RAS Wild-Type Metastatic Colorectal Cancer: The Randomized PANAMA Trial (AIO KRK 0212)
- Nivolumab (NIVO) plus ipilimumab (IPI) vs chemotherapy (chemo) as first-line (1L) treatment for microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC): First results of the CheckMate 8HW study.
- Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer
- NEOPRISM-CRC: Neoadjuvant pembrolizumab stratified to tumour mutation burden for high risk stage 2 or stage 3 deficient-MMR/MSI-high colorectal cancer.